CHIMERAS: MULTI-EPITOPE ANTIGENS

CHIMERAS: MULTI-EPITOPE ANTIGENS

9/9/2019

Chimera

Figure 1. Chimeras

At Rekom Biotech, we have specialized in the design and production of next-generation antigens: chimeras or antigens composed of multiple epitopes, which have improved their antigenic properties, such as sensitivity and specificity. Furthermore, one main advantage of the multi-epitope chimeric antigens is avoiding the use of protein mixtures in your assay. The limited number of binding sites and the different affinities of proteins for these sites could result in reproducibility issues.

EPITOPE ANALYSIS

Epitope analysis

SEQUENCE ANALYSIS

Sequence analysis

3D STUDIES

3D Studies

Rekom Biotech chimeras

DISEASE/ALLERGY

NAME

REFERENCE

DESCRIPTION

Borreliosis or Lyme disease

ChimLyme
(humans)
(animals)

RAG0027 (B. burgdorferi, chimera)

Recombinant chimeric antigen for Borrelia burgdorferi

Chagas

ChimChagas1
(humans)
(animals)

RAG0093 (chimera) img5

Recombinant chimeric antigen for Chagas detection

ChimChagas2
(humans)
(animals)

RAG0094 (chimera) img6

Recombinant chimeric antigen for Chagas detection

ChimChagas3
(humans)
(animals)

RAG0096 (chimera) img7
RAG0096BIOT (biotinylated)

Recombinant chimeric antigen for Chagas detection

Cytomegalovirus

ChimCMV1

RAG0109 (chimera) img8
RAG0109BIOT (biotinylated)

Recombinant chimeric antigen which contains several antigenic determinants for CMV

ChimCMV2

RAG0110 (chimera)
RAG0110BIOT (biotinylated) new

Recombinant chimeric antigen for CMV detection

Syphilis

ChimSyphilis1

RAG0046 (chimera)
RAG0046BIOT (biotinylated)

Recombinant chimeric antigen for Treponema pallidum

ChimSyphilis2

RAG0064 (chimera) new
RAG0064BIOT (biotinylated) new

Recombinant chimeric antigen for Treponema pallidum

Toxoplasmosis

ChimToxo1
(humans)
(animals)

RAG0058 (chimera)

Recombinant chimeric antigen ChimToxo1 for toxoplasmosis detection

Tuberculosis

CFP10:ESAT6
(humans)
(animals)

RAG0060 (chimera)

Recombinant chimeric antigen formed by the proteins CFP10 and ESAT6

Written by Ana Camacho.

CATEGORY: SCIENTIFIC NOTES

 

 
创建时间:2021-02-23 13:24